用脉冲式促黄体生成激素释放激素（LH-RH）治疗隐睾症。

Treatment of cryptorchidism with pulsatile luteinizing hormone-releasing hormone (LH-RH).

作者信息

Keogh E J, MacKellar A, Mallal S A, Dunn A G, McColm S C, Somerville C P, Glatthaar C, Marshall T, Attikiouzel J

出版信息

J Pediatr Surg. 1983 Jun;18(3):282-3. doi: 10.1016/s0022-3468(83)80102-x.

Abstract

This preliminary report describes a new method of treating bilateral cryptorchidism that may modify the need for surgical intervention. Four of five boys (3 1/2, 3 1/2, 7, 11 and 12 1/2 years of age) given hourly subcutaneous pulses of luteinizing hormone-releasing hormone (LH-RH, 10 to 100 micrograms/day, given in a 3-min pulse every hour) showed evidence of testicular descent after 3 to 19 weeks. The battery-operated, programmable syringe driver was well tolerated by the boys, and the daily insertion of the scalp-vein needles was managed at home by their parents.

摘要

本初步报告描述了一种治疗双侧隐睾症的新方法，该方法可能会改变手术干预的必要性。五名男孩（年龄分别为3岁半、3岁半、7岁、11岁和12岁半）每小时接受皮下注射促黄体生成素释放激素（LH-RH，每天10至100微克，每小时以3分钟脉冲方式给药），3至19周后显示出睾丸下降的迹象。男孩们对电池驱动的可编程注射器驱动器耐受性良好，头皮静脉针的每日插入由他们的父母在家中操作。