Brenner S H, Wallach R C
Int J Gynaecol Obstet. 1983 Apr;21(2):167-9. doi: 10.1016/0020-7292(83)90056-5.
A family with benign cystic teratomata in three successive generations is described. Other familial occurrences of these tumors have been reported; but not in three generations. Familial occurrence suggests an inherited characteristic for parthenogenic development and the occurrence of teratomata in twins and triplets supports the theory of a parthenogenic etiology. Benign cystic teratomata may, therefore, be tumors whose origin is genetically controlled.
本文描述了一个三代人中连续出现良性囊性畸胎瘤的家族。此前已有其他关于这些肿瘤家族性发病的报道，但三代连续发病的情况尚未见报道。家族性发病提示孤雌生殖发育具有遗传特征，而双胞胎和三胞胎中出现畸胎瘤则支持孤雌生殖病因学理论。因此，良性囊性畸胎瘤可能是起源受基因控制的肿瘤。
