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垂体柄切断后大鼠垂体中间叶免疫反应性生长抑素的选择性降低

Selective decrease in immunoreactive somatostatin in rat intermediate pituitary lobe after stalk section.

作者信息

Saavedra J M, Rougeot C, Dray F

出版信息

Neuroendocrinology. 1983 Aug;37(2):164-5. doi: 10.1159/000123536.

DOI:10.1159/000123536
PMID:6136931
Abstract

Immunoreactive somatostatin is present in the intermediate pituitary lobe of the rat and, to a lesser extent, in the posterior lobe. Section of the pituitary stalk results in a marked (80%) decrease in somatostatin in the intermediate pituitary lobe, but no change in the peptide levels in the posterior lobe. These results indicate that a substantial part of intermediate lobe somatostatin is located in nerve fibers originated in the brain.

摘要

免疫反应性生长抑素存在于大鼠垂体中间叶,在后叶中含量较少。切断垂体柄会导致垂体中间叶中生长抑素显著减少(80%),但后叶中的肽水平没有变化。这些结果表明,中间叶生长抑素的很大一部分位于起源于脑的神经纤维中。

相似文献

1
Selective decrease in immunoreactive somatostatin in rat intermediate pituitary lobe after stalk section.垂体柄切断后大鼠垂体中间叶免疫反应性生长抑素的选择性降低
Neuroendocrinology. 1983 Aug;37(2):164-5. doi: 10.1159/000123536.
2
Nerve fibers in the rat posterior pituitary lobe contain prosomatostatin (1-64).大鼠垂体后叶中的神经纤维含有前生长抑素(1-64)。
Neuroendocrinology. 1991 Nov;54(5):469-76. doi: 10.1159/000125939.
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Serotonergic innervation of the rat pituitary intermediate lobe: decrease after stalk section.大鼠垂体中间叶的5-羟色胺能神经支配:垂体柄切断后减少。
Endocrinology. 1983 Jun;112(6):1943-7. doi: 10.1210/endo-112-6-1943.
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Somatostatin secretion from the rat neurohypophysis and stalk median eminence (SME) in vitro: calcium-dependent release by high potassium and electrical stimulation.大鼠神经垂体和正中隆起体外生长抑素的分泌:高钾和电刺激引起的钙依赖性释放
Metabolism. 1978 Sep;27(9 Suppl 1):1243-5. doi: 10.1016/0026-0495(78)90052-5.
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Release of endogenous 5-hydroxytryptamine from the neural and the intermediate lobe of the rat pituitary gland evoked by electrical stimulation of the pituitary stalk.垂体柄电刺激诱发大鼠垂体神经叶和中间叶释放内源性5-羟色胺。
Neuroscience. 1985 Jul;15(3):723-8. doi: 10.1016/0306-4522(85)90074-0.
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Differential regulation of tuberohypophysial dopaminergic neurons terminating in the intermediate lobe and in the neural lobe of the rat pituitary gland.大鼠垂体中间叶和神经叶中终末的结节垂体多巴胺能神经元的差异调节。
Neuroendocrinology. 1985 Feb;40(2):145-51. doi: 10.1159/000124066.
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Decreased corticotropin-releasing factor-like immunoreactivity in rat intermediate and posterior pituitary after stalk section.垂体柄切断后大鼠垂体中间部和神经垂体促肾上腺皮质激素释放因子样免疫反应性降低。
Neuroendocrinology. 1984 Jul;39(1):93-5. doi: 10.1159/000123962.
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Somatostatin precursors: evidence for presence in and release from rat median eminence and neurohypophysis.生长抑素前体:大鼠正中隆起和神经垂体中存在及释放的证据。
Biochem Biophys Res Commun. 1979 Sep 27;90(2):466-72. doi: 10.1016/0006-291x(79)91258-0.
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Effect of anterior hypothalamic lesions on neurohypophysial and peripheral tissue concentrations of somatostatin in the rat.下丘脑前部损伤对大鼠神经垂体和外周组织中生长抑素浓度的影响。
Endocrinology. 1979 Sep;105(3):712-5. doi: 10.1210/endo-105-3-712.
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Relationship of the central ACTH-immunoreactive opiocortin system to the median eminence and the pituitary gland of the rat.大鼠中枢促肾上腺皮质激素免疫反应性阿片皮质素系统与正中隆起及垂体的关系。
Cell Tissue Res. 1981;215(2):333-40. doi: 10.1007/BF00239119.

引用本文的文献

1
Immunocytochemical localization of LHRH in the median eminence, infundibular stalk, and neurohypophysis. Evidence for multiple sites of releasing hormone secretion in humans and other mammals.促性腺激素释放激素在正中隆起、漏斗柄和神经垂体中的免疫细胞化学定位。人类和其他哺乳动物中释放激素分泌多部位的证据。
Cell Tissue Res. 1984;236(1):5-14. doi: 10.1007/BF00216506.