Conversion of 2-beta-D-ribofuranosylselenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties. - Suppr | 超能文献

Conversion of 2-beta-D-ribofuranosylselenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties.

作者信息

Jayaram H N, Ahluwalia G S, Dion R L, Gebeyehu G, Marquez V E, Kelley J A, Robins R K, Cooney D A, Johns D G

出版信息

Biochem Pharmacol. 1983 Sep 1;32(17):2633-6. doi: 10.1016/0006-2952(83)90038-2.

DOI:10.1016/0006-2952(83)90038-2

Abstract

摘要

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Conversion of 2-beta-D-ribofuranosylselenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties.

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The conversion of 2-beta-D-ribofuranosylthiazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties.将2-β-D-呋喃核糖基噻唑-4-甲酰胺转化为具有强效肌苷酸脱氢酶抑制特性的烟酰胺腺嘌呤二核苷酸类似物。

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Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity.关于噻唑呋林代谢为具有强大肌苷酸脱氢酶抑制活性的NAD类似物的作用机制的研究。

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引用本文的文献

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Broad-spectrum synergistic antiviral activity of selenazofurin and ribavirin.硒唑呋林与利巴韦林的广谱协同抗病毒活性。

Antimicrob Agents Chemother. 1984 Oct;26(4):466-75. doi: 10.1128/AAC.26.4.466.

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Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses.利巴韦林与C-核苷类似物噻唑呋林和硒唑呋林对披膜病毒、布尼亚病毒和沙粒病毒的协同抗病毒作用。

Antimicrob Agents Chemother. 1984 Oct;26(4):476-80. doi: 10.1128/AAC.26.4.476.

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Effects of selenazofurin and ribavirin and their 5'-triphosphates on replicative functions of influenza A and B viruses.硒唑嘌呤和利巴韦林及其5'-三磷酸酯对甲型和乙型流感病毒复制功能的影响。

Antimicrob Agents Chemother. 1986 Jan;29(1):67-72. doi: 10.1128/AAC.29.1.67.