精神分裂症患者对不同剂量盐酸阿扑吗啡的生长激素反应。
Growth hormone responses to graded doses of apomorphine HCl in schizophrenia.
作者信息
Cleghorn J M, Brown G M, Brown P J, Kaplan R D, Mitton J
出版信息
Biol Psychiatry. 1983 Aug;18(8):875-85.
Growth hormone (GH) responses to graded doses of apomorphine HCl (APO) were established in 14 normal males, ages 18-50, and 10 drug-free schizophrenic (SCZ) subjects; 99% confidence intervals were calculated for normal subjects' GH responses to graded doses of APO. Patients' GH peak levels were found to be outside the interval only when they had positive symptoms of psychosis. When they are actively psychotic, the schizophrenics' GH response to small doses of APO is more sensitive than that of normals.
在14名年龄在18至50岁的正常男性和10名未服用药物的精神分裂症（SCZ）患者中，建立了生长激素（GH）对不同剂量盐酸阿扑吗啡（APO）的反应；计算了正常受试者对不同剂量APO的GH反应的99%置信区间。仅当患者出现精神病阳性症状时，其GH峰值水平才会超出该区间。当精神分裂症患者处于精神病发作期时，他们对小剂量APO的GH反应比正常人更敏感。
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