电感受器的功能与形态：组织学固定过程中的功能

Electroreceptor functioning and morphology: functioning during histological fixation.

作者信息

Eigenhuis C, Doncker J

出版信息

Comp Biochem Physiol A Comp Physiol. 1983;75(4):569-77. doi: 10.1016/0300-9629(83)90422-x.

Abstract

The impact of chemical fixatives on electroreceptor functioning was studied electrophysiologically. The oxidative agents KMnO4 and OsO4 eliminate the sensory response within a few seconds, leaving a disturbed spike train pattern. Glutaraldehyde and formaldehyde eliminate the sensory response gradually in a period of several minutes; after that the afferent fibre shows repetitive activity. It is concluded that the physiological state of the electroreceptor is not preserved during chemical fixation; the ultimate morphological picture will reflect an unphysiological state, i.e. the response to the fixative.

摘要

通过电生理学方法研究了化学固定剂对电感受器功能的影响。氧化剂高锰酸钾（KMnO4）和四氧化锇（OsO4）在几秒钟内消除了感觉反应，留下紊乱的尖峰序列模式。戊二醛和甲醛在几分钟内逐渐消除感觉反应；此后传入纤维表现出重复活动。得出的结论是，在化学固定过程中电感受器的生理状态无法保留；最终的形态学图像将反映一种非生理状态，即对固定剂的反应。