氨甲酰甲胆碱立体异构体对毒蕈碱受体的相对效价。
Relative potencies of the stereoisomers of bethanechol on muscarinic receptor.
作者信息
De Micheli C, De Amici M, Pratesi P, Grana E, Santagostino Barbone M G
出版信息
Farmaco Sci. 1983 Jul;38(7):514-20.
PMID:6137411
Abstract
The two enantiomers and the racemic form of bethanechol have been synthesized and their muscarinic activities evaluated on isolated rat jejunum. The stereoselectivity observed for bethanechol parallels that previously reported for acetyl-beta-methylcholine and muscarine on the same biological object.
摘要
已合成了贝胆碱的两种对映体及其外消旋形式，并在离体大鼠空肠上评估了它们的毒蕈碱活性。观察到的贝胆碱的立体选择性与先前报道的乙酰-β-甲基胆碱和毒蕈碱在同一生物对象上的立体选择性相似。
Zotero 插件