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切断猪睾丸主要血管和神经供应对生精上皮发育的影响。

The effect of transection of the main vascular and nervous supply of the testis on the development of spermatogenic epithelium in the pig.

作者信息

Noordhuizen-Stassen E N, Wensing C J

出版信息

J Pediatr Surg. 1983 Oct;18(5):601-6. doi: 10.1016/s0022-3468(83)80369-8.

DOI:10.1016/s0022-3468(83)80369-8
PMID:6139425
Abstract

The treatment of cryptorchidism in boys by the orchiopexy procedure is variably successful due to several technical problems. In order to study some of these problems a series of experiments in the male pig were undertaken. Experimental simulations of the orchiopexy procedure in the inguinal canal in male pigs with normally descended testes gave rise to damage of the spermatogenic epithelium. Cooling experiments of abdominal testes in adult, naturally cryptorchid pigs indicate that the arrest of spermatogenesis in abdominal testes is not due to an inborn defect but is caused by maintenance of the testes at the abdominal temperature. Evaluation of the data of the interventions with the testicular artery, vein, and nerve, either separately or in combination in the abdomen, showed that there was no effect on the spermatogenic epithelium in any one of the five experimental groups. These experiments confirm that in cryptorchid boys transection of the testicular artery and vein in the abdomen may be indicated if a tension-free fixation of the testis in the scrotum is not achievable, provided that alternate routes are able to take over the main blood supply to the testis.

摘要

由于一些技术问题,通过睾丸固定术治疗男孩隐睾症的成功率各不相同。为了研究其中的一些问题,在雄性猪身上进行了一系列实验。对睾丸正常下降的雄性猪在腹股沟管进行睾丸固定术的实验模拟,导致了生精上皮的损伤。对成年自然隐睾猪的腹腔睾丸进行的降温实验表明,腹腔睾丸精子发生停滞并非由于先天性缺陷,而是由于睾丸维持在腹腔温度所致。对分别或联合对腹部的睾丸动脉、静脉和神经进行干预的数据评估表明,五个实验组中的任何一组对生精上皮均无影响。这些实验证实,如果无法在阴囊内无张力地固定睾丸,在隐睾男孩中,若能有替代途径接管睾丸的主要血液供应,则可考虑切断腹部的睾丸动脉和静脉。

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J Pediatr Surg. 1983 Oct;18(5):601-6. doi: 10.1016/s0022-3468(83)80369-8.
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