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Naphthalenesulfonamides as calmodulin antagonists.

作者信息

Hidaka H, Tanaka T

出版信息

Methods Enzymol. 1983;102:185-94. doi: 10.1016/s0076-6879(83)02019-4.

DOI:10.1016/s0076-6879(83)02019-4
PMID:6139736
Abstract
摘要

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Naphthalenesulfonamides as calmodulin antagonists.萘磺酰胺类作为钙调蛋白拮抗剂。
Methods Enzymol. 1983;102:185-94. doi: 10.1016/s0076-6879(83)02019-4.
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[Inhibitor of calmodulin and calmodulin dependent enzyme].
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Amiodarone is a potent calmodulin antagonist.胺碘酮是一种有效的钙调蛋白拮抗剂。
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Inhibition of calmodulin-dependent calcium-ATPase and phosphodiesterase by various cyclopeptides and peptide alkaloids from the Zizyphus species.枣属植物中各种环肽和肽生物碱对钙调蛋白依赖性钙-ATP酶和磷酸二酯酶的抑制作用。
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Evidence that tamoxifen binds to calmodulin in a conformation different to that when binding to estrogen receptors, through structure-activity study on ring-fused analogues.通过对稠环类似物的构效关系研究发现,他莫昔芬以一种与结合雌激素受体时不同的构象与钙调蛋白结合的证据。
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