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[炎症性动脉病的解剖病理学。巨细胞动脉炎的特殊方面]

[Anatomopathology of inflammatory arteriopathies. Peculiar aspects of giant cell arteritis].

作者信息

Chomette G, Auriol M, Tranbaloc P

出版信息

Ann Med Interne (Paris). 1983;134(5):421-7.

PMID:6139972
Abstract

The authors discuss a large series of biopsy and necropsy findings in patients with giant cell arteritis (Buerger's thromboangiitis, Horton and Takayasu's diseases), and then in patients with other forms of arteritis with an inconstant plasmodial factor, such as the Chürg and Strauss syndrome, Wegener's disease, the pseudo-sarcoidosis form of lymphomatoid granulomatosis. The histology, correlated when necessary with ain immunofluorescent study, was completed by a topographical and evolutional study of the lesions in all cases. The pathogenesis of these different forms of arteritis is discussed in the light of the ultrastructural data concerning the formation of the various types of giant cell and the methods of identification of the vascular walls.

摘要

作者讨论了巨细胞动脉炎(伯格氏血栓性血管炎、霍顿病和高安氏病)患者的大量活检和尸检结果,接着讨论了其他形式的动脉炎患者的情况,这些动脉炎存在不恒定的疟原虫样因子,如变应性肉芽肿性血管炎、韦格纳肉芽肿病、淋巴瘤样肉芽肿病的假结节病形式。在所有病例中,组织学(必要时与免疫荧光研究相关联)通过对病变的局部解剖和演变研究得以完善。根据有关各类巨细胞形成的超微结构数据以及血管壁的识别方法,对这些不同形式动脉炎的发病机制进行了讨论。

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