Tanaka T, Sakuragi N, Fujimoto S, Ichinoe K, Mizoe J
Int J Fertil. 1983;28(3):184-7.
Multiple gestations after human menopausal gonadotropin (hMG)-human chorionic gonadotropin (hCG) therapy were detected within 7 gestational weeks (GW) by ultrasound examinations and also by "midluteal phase" (MLP) progesterone (P) concentrations. The mean MLP-P level in nonconception cycles following hMG-hCG therapy was 25.1 +/- 2.1 ng/ml. In the pregnancies following hMG-hCG therapy, MLP-P levels were 32 ng/ml, 37 ng/ml, and 56 ng/ml. These values were associated with a singleton, twin, and triplet pregnancies, respectively. Ultrasonography revealed the number of gestational sacs within 7 GW in each instance. We suggest that assay of MLP-P is useful in women receiving regimens for induction of ovulation. Efforts may as well be made to ascertain multiple conceptions by ultrasound examinations in patients whose MLP-P levels are far above the mean MLP-P level in hMG-hCG-induced cycles.
通过超声检查以及“黄体中期”（MLP）孕酮（P）浓度检测，发现在人绝经期促性腺激素（hMG）-人绒毛膜促性腺激素（hCG）治疗后7孕周（GW）内出现多胎妊娠。hMG-hCG治疗后未受孕周期的平均MLP-P水平为25.1±2.1 ng/ml。在hMG-hCG治疗后的妊娠中，MLP-P水平分别为32 ng/ml、37 ng/ml和56 ng/ml。这些值分别与单胎、双胎和三胎妊娠相关。超声检查在每种情况下均于7 GW内显示出妊娠囊的数量。我们建议，MLP-P测定对于接受诱导排卵方案的女性有用。对于MLP-P水平远高于hMG-hCG诱导周期中平均MLP-P水平的患者，也应努力通过超声检查确定多胎妊娠情况。
