Saarma J
Psychiatr Neurol Med Psychol (Leipz). 1983 Oct;35(10):587-97.
The results of our follow-up studies show that; Active methods of treatment have improved the direct results of treatment for schizophrenics distinctly; the number of cured patients has increased three to four-fold, and the number of patients who are immune to treatment has even diminished by factor of 10. The results of active methods of treatment are not stable in the long term; in the course of our observations the number of cured decreased and the number of severely ill increased. Despite the inadequate stability of the cures resulting from treatment, the long-term prognosis is better for those who received active treatment than for those treated passively. Schizophrenics treated with insulin during their first term of hospitalization have a better chance of being cured permanently. The results presented here show that clearly differentiated indications must be elaborated for all methods currently used to treat schizophrenia in order to obtain optimum results.
积极的治疗方法显著改善了精神分裂症患者的直接治疗效果;治愈患者的数量增加了三到四倍,对治疗无反应的患者数量甚至减少到原来的十分之一。积极治疗方法的效果从长期来看并不稳定;在我们的观察过程中,治愈的患者数量减少,重症患者数量增加。尽管治疗带来的治愈效果稳定性不足,但接受积极治疗的患者长期预后仍优于接受被动治疗的患者。在首次住院期间接受胰岛素治疗的精神分裂症患者有更好的机会被永久治愈。此处呈现的结果表明,为了获得最佳效果,必须为目前用于治疗精神分裂症的所有方法制定明确区分的适应症。