Suppr超能文献

二氮杂卓类的化学结构与生物活性。

Chemical structure and biological activity of the diazepines.

作者信息

Danneberg P, Weber K H

出版信息

Br J Clin Pharmacol. 1983;16 Suppl 2(Suppl 2):231S-244S. doi: 10.1111/j.1365-2125.1983.tb02295.x.

Abstract

Since the introduction of chlordiazepoxide and diazepam many diazepines have been developed. Use of these drugs is increasing and considerable knowledge has accumulated about their mechanisms of action. The structural and pharmacological properties of these drugs are surveyed briefly.

摘要

自从氯氮卓和地西泮问世以来,已开发出许多苯二氮䓬类药物。这些药物的使用正在增加,并且已经积累了大量关于其作用机制的知识。本文简要概述了这些药物的结构和药理特性。

相似文献

1
Chemical structure and biological activity of the diazepines.
Br J Clin Pharmacol. 1983;16 Suppl 2(Suppl 2):231S-244S. doi: 10.1111/j.1365-2125.1983.tb02295.x.
2
Pharmacodynamics of benzodiazepines.
S Afr Med J. 1985 Oct 26;Suppl:14-22.
3
The biological basis of benzodiazepine actions.
J Psychoactive Drugs. 1983 Jan-Jun;15(1-2):19-39. doi: 10.1080/02791072.1983.10472119.
4
Anxiety.
Lancet. 1982 Nov 6;2(8306):1030-4. doi: 10.1016/s0140-6736(82)90059-9.
5
Brain mechanisms associated with therapeutic actions of benzodiazepines: focus on neurotransmitters.
Am J Psychiatry. 1977 Jun;134(6):662-5. doi: 10.1176/ajp.134.6.662.
9
Benzodiazepines and neurotic anxiety. Critique.
N Y State J Med. 1976 Dec;76(13):2156-64.
10
Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and gamma-aminobutyric acid systems.
Psychopharmacology (Berl). 2002 Oct;163(3-4):434-58. doi: 10.1007/s00213-002-1139-6. Epub 2002 Aug 6.

引用本文的文献

1
One-pot synthesis and pharmacological evaluation of new quinoline/pyrimido-diazepines as pulmonary antifibrotic agents.
Future Med Chem. 2024;16(21):2211-2230. doi: 10.1080/17568919.2024.2394018. Epub 2024 Sep 18.
3
Review of withdrawal catatonia: what does this reveal about clozapine?
Transl Psychiatry. 2018 Jul 31;8(1):139. doi: 10.1038/s41398-018-0192-9.
4
Synthesis and anticonvulsant activity of various mannich and schiff bases of 1,5-benzodiazepines.
Int J Med Chem. 2012;2012:237965. doi: 10.1155/2012/237965. Epub 2012 Nov 28.

本文引用的文献

1
The psychosedative properties of methaminodiazepoxide.
J Pharmacol Exp Ther. 1960 Jun;129:163-71.
2
Effects of psychotropic drugs on limbic system of cat.
Proc Soc Exp Biol Med. 1960 Oct;105:115-7. doi: 10.3181/00379727-105-26028.
4
Electrophysiological studies on the specific benzodiazepine antagonist Ro 15-1788.
Naunyn Schmiedebergs Arch Pharmacol. 1981 Jul;316(4):317-25. doi: 10.1007/BF00501364.
5
The central GABAergic system and control of food intake under different experimental conditions.
Psychopharmacology (Berl). 1980;68(2):163-7. doi: 10.1007/BF00432135.
6
Benzodiazepine receptor-mediated experimental "anxiety" in primates.
Science. 1982 Dec 24;218(4579):1332-4. doi: 10.1126/science.6293059.
7
Selective antagonists of benzodiazepines.
Nature. 1981 Apr 9;290(5806):514-6. doi: 10.1038/290514a0.
9
Kainic acid differentiates GABA receptors from benzodiazepine receptors in the rat cerebellum.
Brain Res. 1980 Jul 14;193(2):589-93. doi: 10.1016/0006-8993(80)90195-x.
10
Benzodiazepine receptor protein identified and visualized in brain tissue by a photoaffinity label.
Proc Natl Acad Sci U S A. 1980 Mar;77(3):1666-70. doi: 10.1073/pnas.77.3.1666.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验