催眠药与呼吸控制：综述

Br J Clin Pharmacol. 1983;16 Suppl 2(Suppl 2):245S-250S. doi: 10.1111/j.1365-2125.1983.tb02296.x.

Hypnotics are central depressants. In sufficient doses, they suppress respiration, and so their effects on respiration are important considerations in their safety. The paper reviews mechanisms of respiratory control and methods of assessment, the effects of hypnotics on control of breathing and new methods of non-invasive respiratory monitoring.

催眠药是中枢抑制剂。剂量足够时，它们会抑制呼吸，因此其对呼吸的影响是考量其安全性的重要因素。本文综述了呼吸控制机制及评估方法、催眠药对呼吸控制的影响以及无创呼吸监测的新方法。

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Hypnotics and the control of breathing: a review.

Br J Clin Pharmacol. 1983;16 Suppl 2(Suppl 2):245S-250S. doi: 10.1111/j.1365-2125.1983.tb02296.x.

Central nervous respiratory depressants--anesthetics, hypnotics, sedatives and other respiratory depressants.

Pharmacol Ther B. 1978;3(3):377-95. doi: 10.1016/s0306-039x(78)80003-8.

Breathing during exercise.

N Engl J Med. 1978 Apr 6;298(14):780-5. doi: 10.1056/NEJM197804062981408.

Pharmacological effects of sedative-hypnotics, narcotic analgesics, and alcohol during sleep.

Med Clin North Am. 1985 Nov;69(6):1281-8. doi: 10.1016/s0025-7125(16)30987-7.

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Pharmacol Ther B. 1976;2(4):717-41. doi: 10.1016/0306-039x(76)90075-1.

[Review: physiology of respiration (1975--1978)].

Fiziol Zh SSSR Im I M Sechenova. 1979 Jan;65(1):3-14.

Self-injection of barbiturates, benzodiazepines and other sedative-anxiolytics in baboons.

NIDA Res Monogr. 1990;105:329.

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Clin Neurosurg. 1975;22:444-61. doi: 10.1093/neurosurgery/22.cn_suppl_1.444.

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A comparison of the effects of zolpidem and placebo on respiration and oxygen saturation during sleep in the healthy elderly.

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Respiration and wakefulness in man.

Acta Physiol Scand Suppl. 1963;209:1-110.

Changes in respiratory response to CO2 during natural sleep at sea level and at altitude.

J Appl Physiol. 1958 Nov;13(3):325-30. doi: 10.1152/jappl.1958.13.3.325.

Changes in ventilation and chest wall mechanics during sleep in normal adolescents.

J Appl Physiol Respir Environ Exerc Physiol. 1981 Sep;51(3):557-64. doi: 10.1152/jappl.1981.51.3.557.

Some recent advances in the study of the control of breathing in patients with chronic obstructive lung disease.

Anesth Analg. 1980 Nov;59(11):865-73.

Respiratory and psychological effects of oral temazepam in volunteers.

Br J Anaesth. 1980 Sep;52(9):901-6. doi: 10.1093/bja/52.9.901.

A clinical method for assessing the ventilatory response to carbon dioxide.

Australas Ann Med. 1967 Feb;16(1):20-32. doi: 10.1111/imj.1967.16.1.20.

The effect of chlordiazepoxide and pethidine, alone and in combination, on the respiratory response to carbon dioxide.

Br J Anaesth. 1967 Jun;39(6):459-63. doi: 10.1093/bja/39.6.459.

Patterns of ventilatory response to carbon dioxide during recovery from severe asthma.

Clin Sci. 1971 Jul;41(1):13-21. doi: 10.1042/cs0410013.

Changes in tidal volume, frequency, and ventilation induced by their measurement.

J Appl Physiol. 1972 Aug;33(2):252-4. doi: 10.1152/jappl.1972.33.2.252.

Genetic differences in the ventilatory response to inhaled CO2.

J Appl Physiol. 1974 Jan;36(1):6-11. doi: 10.1152/jappl.1974.36.1.6.

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Br J Clin Pharmacol. 1983;16 Suppl 2(Suppl 2):245S-250S. doi: 10.1111/j.1365-2125.1983.tb02296.x.

相似文献

Hypnotics and the control of breathing: a review.

Br J Clin Pharmacol. 1983;16 Suppl 2(Suppl 2):245S-250S. doi: 10.1111/j.1365-2125.1983.tb02296.x.

Central nervous respiratory depressants--anesthetics, hypnotics, sedatives and other respiratory depressants.

Pharmacol Ther B. 1978;3(3):377-95. doi: 10.1016/s0306-039x(78)80003-8.

Breathing during exercise.

N Engl J Med. 1978 Apr 6;298(14):780-5. doi: 10.1056/NEJM197804062981408.

Pharmacological effects of sedative-hypnotics, narcotic analgesics, and alcohol during sleep.

Med Clin North Am. 1985 Nov;69(6):1281-8. doi: 10.1016/s0025-7125(16)30987-7.

The effects of psychotropic drugs on respiration.

Pharmacol Ther B. 1976;2(4):717-41. doi: 10.1016/0306-039x(76)90075-1.

[Review: physiology of respiration (1975--1978)].

Fiziol Zh SSSR Im I M Sechenova. 1979 Jan;65(1):3-14.

Self-injection of barbiturates, benzodiazepines and other sedative-anxiolytics in baboons.

NIDA Res Monogr. 1990;105:329.

Ventilation of the neurosurgical patient.

Clin Neurosurg. 1975;22:444-61. doi: 10.1093/neurosurgery/22.cn_suppl_1.444.

Integration of peripheral and central chemoreceptor stimuli by pontine and medullary respiratory centers.

Fed Proc. 1977 Sep;36(10):2421-7.

Regulation of respiration (first of three parts).

N Engl J Med. 1977 Jul 14;297(2):92-7. doi: 10.1056/NEJM197707142970206.

引用本文的文献

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Pharmacology of ramelteon, a selective MT1/MT2 receptor agonist: a novel therapeutic drug for sleep disorders.

CNS Neurosci Ther. 2009 Winter;15(1):32-51. doi: 10.1111/j.1755-5949.2008.00066.x.

The use of psychotropics in the medically ill.

Curr Psychiatry Rep. 2000 Jun;2(3):247-55. doi: 10.1007/s11920-996-0018-y.

Drugs and brain death.

Drug Saf. 1996 Mar;14(3):171-80. doi: 10.2165/00002018-199614030-00004.

Effects of zolpidem, codeine phosphate and placebo on respiration. A double-blind, crossover study in volunteers.

Drug Saf. 1993 Oct;9(4):312-9. doi: 10.2165/00002018-199309040-00009.

Pharmacotherapy of insomnia: practice and prospects.

Pharm World Sci. 1995 May 26;17(3):67-75. doi: 10.1007/BF01875434.

Guidelines for the rational use of benzodiazepines. When and what to use.

Drugs. 1994 Jul;48(1):25-40. doi: 10.2165/00003495-199448010-00004.

Effects of diazepam and chlormethiazole on ventilatory control in normal subjects.

Br J Clin Pharmacol. 1988 Jun;25(6):766-70. doi: 10.1111/j.1365-2125.1988.tb05266.x.

A comparison of the effects of zolpidem and placebo on respiration and oxygen saturation during sleep in the healthy elderly.

Br J Clin Pharmacol. 1990 Dec;30(6):817-24. doi: 10.1111/j.1365-2125.1990.tb05446.x.

本文引用的文献

Respiration and wakefulness in man.

Acta Physiol Scand Suppl. 1963;209:1-110.

Changes in respiratory response to CO2 during natural sleep at sea level and at altitude.

J Appl Physiol. 1958 Nov;13(3):325-30. doi: 10.1152/jappl.1958.13.3.325.

Changes in ventilation and chest wall mechanics during sleep in normal adolescents.

J Appl Physiol Respir Environ Exerc Physiol. 1981 Sep;51(3):557-64. doi: 10.1152/jappl.1981.51.3.557.

Some recent advances in the study of the control of breathing in patients with chronic obstructive lung disease.

Anesth Analg. 1980 Nov;59(11):865-73.

Respiratory and psychological effects of oral temazepam in volunteers.

Br J Anaesth. 1980 Sep;52(9):901-6. doi: 10.1093/bja/52.9.901.

A clinical method for assessing the ventilatory response to carbon dioxide.

Australas Ann Med. 1967 Feb;16(1):20-32. doi: 10.1111/imj.1967.16.1.20.

The effect of chlordiazepoxide and pethidine, alone and in combination, on the respiratory response to carbon dioxide.

Br J Anaesth. 1967 Jun;39(6):459-63. doi: 10.1093/bja/39.6.459.

Patterns of ventilatory response to carbon dioxide during recovery from severe asthma.

Clin Sci. 1971 Jul;41(1):13-21. doi: 10.1042/cs0410013.

Changes in tidal volume, frequency, and ventilation induced by their measurement.

J Appl Physiol. 1972 Aug;33(2):252-4. doi: 10.1152/jappl.1972.33.2.252.

Genetic differences in the ventilatory response to inhaled CO2.

J Appl Physiol. 1974 Jan;36(1):6-11. doi: 10.1152/jappl.1974.36.1.6.

Hypnotics and the control of breathing: a review.

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催眠药与呼吸控制：综述

Hypnotics and the control of breathing: a review.

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