Svedmyr N
Eur J Respir Dis Suppl. 1983;131:313-29.
At present there is no study indicating that any drug can decrease "primary hyperreactivity". If the frequency of asthma attacks can be lowered this seems to cause a decrease of the induced (?) hyperreactivity. This is proven for DCG and gold and may also be true for steroids and perhaps for other effective anti-asthmatic drugs. The mechanism is probably a decrease of the inflammatory reaction in the bronchial mucosa due to less frequent and less severe asthma attacks.
目前尚无研究表明任何药物可降低“原发性高反应性”。如果哮喘发作频率能够降低,似乎会导致诱发性(?)高反应性下降。这已在二醋二氟拉松和金制剂中得到证实,对类固醇或许还有其他有效的抗哮喘药物可能也适用。其机制可能是由于哮喘发作频率降低且严重程度减轻,导致支气管黏膜炎症反应减弱。