Tsakok F H, Koh S, Ilancheran A, Poh W K, Ratnam S S
Int J Gynaecol Obstet. 1983 Dec;21(6):485-90. doi: 10.1016/0020-7292(83)90040-1.
Three maternal deaths with hydatidiform molar pregnancies associated with severe hemorrhage and coagulopathy are described. Symptoms of coagulation abnormalities are few in mild degrees of intravascular coagulation. This paper addresses the importance of anticipating a coagulopathy in hydatidiform molar pregnancy even before evacuation of the abnormal conceptus since evacuation aggravates fibrinolytic activity and therefore increases hemorrhage in these conditions.
本文描述了三例葡萄胎妊娠合并严重出血和凝血病导致的孕产妇死亡。在轻度血管内凝血时，凝血异常的症状较少。本文强调了即使在清除异常妊娠物之前，就应预见到葡萄胎妊娠中凝血病的重要性，因为清除妊娠物会加剧纤溶活性，从而增加这些情况下的出血。
