Tringali G R, Montenegro M R, Walker D H, Mansueto S
Acta Trop. 1983 Dec;40(4):311-20.
Immunity to rickettsiae is enhanced by both T-lymphocytes and humoral antibodies; however, the principal effector of rickettsial killing is the macrophage. Lymphokines may play an important role. There is undoubtedly a complex in vivo interaction between the immune, phagocytic, and inflammatory host defenses against these obligate intracellular bacteria.
T淋巴细胞和体液抗体均可增强对立克次体的免疫力;然而,杀死立克次体的主要效应细胞是巨噬细胞。淋巴因子可能起重要作用。在针对这些专性细胞内细菌的免疫、吞噬和炎症性宿主防御之间,无疑存在着复杂的体内相互作用。