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[成年大鼠酶系统和激素系统功能状态变化之间的相关性]

[Correlation between the changes in the functional state of enzyme and hormonal systems of the mature rat].

作者信息

Merkur'eva R V, Ozolinia A Zh, Astakhova L F, Dolinskaia S I, Bektemirova R M

出版信息

Vopr Med Khim. 1984 Jan-Feb;30(1):34-7.

PMID:6143450
Abstract

Content of progesterone and cortisol was studied in blood plasma. Activities of organelle-specific enzymes were estimated in mitochondria (malate dehydrogenase, glutamate dehydrogenase, H + ATPase) and in endoplasmic reticulum (inosine-5-diphosphatase) of liver, kidney tissues and blood serum of rats, which were born after the influence of embryotoxic effectors. Correlation was found in alterations of the patterns studied. The steroid hormonal systems appear to affect the stability of mitochondrial and microsomal membranes in liver and kidney tissues of experimental animals.

摘要

研究了血浆中孕酮和皮质醇的含量。对受胚胎毒性效应物影响后出生的大鼠的肝脏、肾脏组织及血清中的线粒体(苹果酸脱氢酶、谷氨酸脱氢酶、H⁺ATP酶)和内质网(肌苷-5-二磷酸酶)中的细胞器特异性酶活性进行了评估。在所研究的模式变化中发现了相关性。类固醇激素系统似乎会影响实验动物肝脏和肾脏组织中线粒体和微粒体膜的稳定性。

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