Ariel M, Lasater E M, Mangel S C, Dowling J E
Brain Res. 1984 Mar 12;295(1):179-83. doi: 10.1016/0006-8993(84)90828-x.
Threshold concentrations for L-glutamate, L-aspartate and their agonists, kainate, quisqualate and N-methyl-D,L-aspartate, were determined for horizontal cells of the intact carp retina and horizontal cells that were enzymatically isolated and maintained in culture. Our results indicate that uptake or other mechanisms decrease the apparent sensitivity of these cells in the intact retina to L-glutamate by 25-200 times. Our findings also suggest that L-glutamate is more likely a photoreceptor transmitter than L-aspartate.
测定了完整鲤鱼视网膜水平细胞以及经酶解分离并培养的水平细胞对L-谷氨酸、L-天冬氨酸及其激动剂红藻氨酸、quisqualate和N-甲基-D,L-天冬氨酸的阈值浓度。我们的结果表明，摄取或其他机制使这些细胞在完整视网膜中对L-谷氨酸的表观敏感性降低了25至200倍。我们的研究结果还表明，L-谷氨酸比L-天冬氨酸更有可能是光感受器递质。
