Sato T, Hiramatsu R, Iwaoka T, Fujii Y, Shimada T, Umeda T
Tohoku J Exp Med. 1984 Feb;142(2):195-200. doi: 10.1620/tjem.142.195.
In order to identify non-endocrine laboratory tests of diagnostic value in Cushing's syndrome, we measured platelet counts and serum myogenic and hepatic enzyme levels in 10 patients with Cushing's syndrome and compared the findings with those of 15 obese patients without Cushing's syndrome. Patients with Cushing's syndrome had increased numbers of platelets, moderately elevated serum lactic dehydrogenase and gamma-glutamyltranspeptidase levels, and significantly lower creatine phosphokinase and choline esterase activities compared with those of obese control patients. We concluded that when several of these abnormal values were seen in obese patients the levels of suspicion for Cushing's syndrome should be high.
为了确定库欣综合征中具有诊断价值的非内分泌实验室检查，我们对10例库欣综合征患者进行了血小板计数以及血清肌源性和肝酶水平的测定，并将结果与15例无库欣综合征的肥胖患者进行比较。与肥胖对照患者相比，库欣综合征患者的血小板数量增加，血清乳酸脱氢酶和γ-谷氨酰转肽酶水平中度升高，肌酸磷酸激酶和胆碱酯酶活性显著降低。我们得出结论，当在肥胖患者中出现这些异常值中的几个时，对库欣综合征的怀疑程度应该很高。
