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青蛙视网膜的谷氨酸分离质量受体电位。I. 一般特性及强度依赖性

The glutamate-isolated mass receptor potential of the frog's retina. I. General properties and intensity dependence.

作者信息

Reichenbach A

出版信息

Biomed Biochim Acta. 1983;42(10):1269-76.

PMID:6144306
Abstract

The glutamate-isolated mass receptor potential of the superfused frog's retina was investigated in order to find a method for discrimination of both rod and cone contribution to the sum response. After mesopic white light stimuli the potential showed a biphasic decay with a rapid and a slow part, respectively. Regarding threshold, saturation, light adaptation, and time course, the rapid decay is shown to correspond to the cone response. The remaining part of mass receptor potential, on the other hand, resembled the rod response in all these properties. This analysis provides the basis for studying the cation dependence of rod and cone receptor potentials with the stable mass receptor potentials. Moreover, the time course of the rod's light response is discussed to draw some conclusions regarding the internal transmission in rod photoreceptors.

摘要

为了找到一种区分视杆细胞和视锥细胞对总和反应贡献的方法,研究了灌流青蛙视网膜的谷氨酸分离质量受体电位。在中明视觉白光刺激后,该电位呈现双相衰减,分别有快速和缓慢部分。就阈值、饱和度、光适应和时间进程而言,快速衰减部分被证明对应于视锥细胞反应。另一方面,质量受体电位的其余部分在所有这些特性上都类似于视杆细胞反应。该分析为利用稳定的质量受体电位研究视杆细胞和视锥细胞受体电位的阳离子依赖性提供了基础。此外,还讨论了视杆细胞光反应的时间进程,以得出关于视杆细胞光感受器内部信号传递的一些结论。

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