Brown R P, Kocsis J H
Hosp Community Psychiatry. 1984 May;35(5):486-91. doi: 10.1176/ps.35.5.486.
Antipsychotic drug use may be associated with clinically significant cardiovascular side effects and rare instances of sudden death. The authors review case reports of patients who suddenly died while taking these drugs and examine possible mechanisms involved. Clinical recommendations for prevention are made and include attention to predisposing medical factors and avoidance of risky drug combinations.
使用抗精神病药物可能会产生具有临床意义的心血管副作用,以及罕见的猝死案例。作者回顾了服用这些药物期间突然死亡的患者的病例报告,并研究了其中可能涉及的机制。同时给出了预防的临床建议,包括关注诱发疾病的医学因素以及避免使用有风险的药物组合。