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腹腔注射和脑池内注射后,蝎子、海葵、蛇和蜂毒毒素对小鼠的致死效力。

Lethal potency in mice of toxins from scorpion, sea anemone, snake and bee venoms following intraperitoneal and intracisternal injection.

作者信息

Schweitz H

出版信息

Toxicon. 1984;22(2):308-11. doi: 10.1016/0041-0101(84)90032-1.

DOI:10.1016/0041-0101(84)90032-1
PMID:6145236
Abstract

The lethal potency of 29 toxins from scorpion, sea anemone, snake and bee venoms was studied. Lethality following intracisternal injection of these toxins is considerably higher than following i.p. injection (except for the snake neurotoxins). This is of practical interest in the determination of the concentration of active toxins in a solution when only small amounts are available, as in the case of radiolabelled toxins.

摘要

对来自蝎子、海葵、蛇和蜜蜂毒液的29种毒素的致死效力进行了研究。脑池内注射这些毒素后的致死率远高于腹腔注射(蛇神经毒素除外)。当只有少量毒液(如放射性标记毒素的情况)时,这对于测定溶液中活性毒素的浓度具有实际意义。

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