Avakyan A A, Popov V L
Acta Virol. 1984 Mar;28(2):159-73.
The structure and cytopathology of obligate intracellular bacteria belonging to families Rickettsiaceae and Chlamydiaceae and their interaction with eukaryotic host cells were compared in electron microscopic studies. "Rickettsia-like" and "chlamydia-like" types of organization of bacterial cells and their interaction with host cells are presented. The rickettsia-like type is characterized by short rod-shaped cells multiplying freely ( extravacuolarly ) in the cytoplasm or nucleoplasm of the host cell; the chlamydia-like type has spherical cells multiplying inside the cytoplasmic vacuole limited by the host membrane. The rickettsia-like type includes the genus Rickettsia and rod-shaped symbionts from genera Wolbachia and Symbiotes ; the chlamydia-like type falls into genera Chlamydia, Ehrlichia, Cowdria and Neorickettsia . The transitional types represented by Wolbachia persica (type 1), Coxiella and Rickettsiella (type 2) are also described. The possible evolutional relationships of the genera comprising both families are considered and their classification is proposed.
在电子显微镜研究中，对属于立克次氏体科和衣原体科的专性细胞内细菌的结构和细胞病理学及其与真核宿主细胞的相互作用进行了比较。文中呈现了细菌细胞的“类立克次氏体”和“类衣原体”组织类型及其与宿主细胞的相互作用。类立克次氏体类型的特征是短杆状细胞在宿主细胞的细胞质或核质中自由繁殖（胞外繁殖）；类衣原体类型有球形细胞，在由宿主膜界定的细胞质液泡内繁殖。类立克次氏体类型包括立克次氏体属以及来自沃尔巴克氏体属和共生体属的杆状共生体；类衣原体类型包括衣原体属、埃立克体属、考德里氏体属和新立克次氏体属。还描述了以波斯沃尔巴克氏体（1型）、柯克斯氏体和立克次氏体属（2型）为代表的过渡类型。文中考虑了这两个科所属各属可能的进化关系，并提出了它们的分类。
