Aldenhoff J B, Lux H D
Fortschr Neurol Psychiatr. 1984 May;52(5):152-63. doi: 10.1055/s-2007-1002013.
The action of lithium on cellular calcium regulation has been observed in snail neurons using electrophysiological methods. Recently, calcium-dependent mechanisms are thought to play a central role in the integrative functions of the CNS. The coupling between humoral and electrical effects of neurons by calcium iones appears to be especially interesting in respect of the clinical actions of lithium. Here we discuss clinical and experimental studies considering the question if the well known effects of lithium therapy could be produced by an action of lithium on the calcium regulation of nerve cells.
利用电生理方法在蜗牛神经元中观察到了锂对细胞钙调节的作用。近来，钙依赖机制被认为在中枢神经系统的整合功能中起核心作用。就锂的临床作用而言，钙离子介导的神经元体液效应与电效应之间的耦合似乎特别有趣。在此，我们讨论临床和实验研究，探讨锂疗法的已知效应是否可能由锂对神经细胞钙调节的作用所产生。
