David T J, Wybrew M, Hennessen U
Lancet. 1984 Jul 21;2(8395):154-5. doi: 10.1016/s0140-6736(84)91060-2.
In a prospective study of 79 children with asthma, 26 had prodromal itching 1 - 30 min before the attack, and 17 had prodromal itching during the early part of the attack. The sensation lasted up to about 30 min. Scratch marks were seen in 5 patients. In 7 patients the itching was known to the child but had not been recognised by the parents. The site of itching was constant for each patient, being the anterior part of the neck in 14 patients and the upper part of the back in 9 patients. The pathogenesis of prodromal itching is obscure, but its recognition may be of diagnostic use when taking a history and may enable an attack of asthma to be aborted or treated more promptly.
在一项针对79名哮喘患儿的前瞻性研究中,26名患儿在发作前1至30分钟出现前驱性瘙痒,17名患儿在发作初期出现前驱性瘙痒。这种感觉持续长达约30分钟。5名患者身上可见抓痕。7名患儿知道自己瘙痒,但家长未意识到。每位患者的瘙痒部位固定,14名患者为颈部前部,9名患者为背部上部。前驱性瘙痒的发病机制尚不清楚,但其识别在问诊时可能具有诊断价值,并且可能使哮喘发作得以中止或得到更及时的治疗。