生长抑素对磷蛋白磷酸酶的调节作用。
Regulation of phosphoprotein phosphatase by somatostatin.
作者信息
Catalan R E, Miguel B G, Godoy J E, Robles A, Aragones M D, Martinez A M
出版信息
Biochem Med. 1984 Feb;31(1):36-41. doi: 10.1016/0006-2944(84)90056-5.
PMID:6146316
Abstract
Cyclic somatostatin inhibited phosphoprotein phosphatase activity in rat liver slices, as well as a partially purified phosphoprotein phosphatase from rat liver. This change was accompanied by a concomitant decrease in cyclic AMP-dependent protein kinase. Studies in vivo showed similar trends in the variation of both enzymes.
摘要
环磷生长抑素抑制大鼠肝切片中的磷蛋白磷酸酶活性，以及来自大鼠肝脏的部分纯化的磷蛋白磷酸酶。这种变化伴随着环磷酸腺苷依赖性蛋白激酶的相应减少。体内研究显示这两种酶的变化有相似趋势。
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