冬眠动物球旁细胞的超微结构与生化参数的相关性

Ultrastructure of juxtaglomerular cells correlated with biochemical parameters in a hibernator.

作者信息

Zimny M L, Franco E E, St Onge M, Pearson J

出版信息

Comp Biochem Physiol A Comp Physiol. 1984;78(2):229-35. doi: 10.1016/0300-9629(84)90137-3.

Abstract

Ultrastructural features of juxtaglomerular cells have been correlated with plasma and kidney analyses from non-hibernating, hibernating and awakening ground squirrels. Juxtaglomerular cells in kidneys from hibernating animals show signs of increased activity. Plasma samples from hibernating animals show a significant increase in magnesium. Kidney analyses from hibernating animals, show glycogen increases and lactate and inorganic phosphate decrease significantly. Adenosine triphosphate remains the same. Maintenance of high-energy phosphates in the hibernating kidney is essential to maintaining sodium transport and osmotic pressure. This coupled with a functional renin-angiotensin system regulates water and electrolyte balance.

摘要

肾小球旁细胞的超微结构特征已与非冬眠、冬眠和苏醒地松鼠的血浆及肾脏分析相关联。冬眠动物肾脏中的肾小球旁细胞显示出活性增加的迹象。冬眠动物的血浆样本显示镁含量显著增加。对冬眠动物肾脏的分析表明，糖原增加，乳酸和无机磷酸盐显著减少。三磷酸腺苷保持不变。冬眠肾脏中高能磷酸盐的维持对于维持钠转运和渗透压至关重要。这与功能性肾素-血管紧张素系统一起调节水和电解质平衡。