丁基羟基甲苯对大鼠肝脏谷胱甘肽S-转移酶亚基诱导的比较效应
Comparative effect of the induction of the subunits of rat liver glutathione S-transferases by butylated hydroxytoluene.
作者信息
Awasthi Y C, Partridge C A, Theodore C, Dao D D
出版信息
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1984;78(1):39-41. doi: 10.1016/0742-8413(84)90044-6.
PMID:6146480
Abstract
When butylated hydroxytoluene (BHT) was administered to rats, the smallest subunit Ya (Mr 22,000) of rat liver GSH S-transferases was found to undergo maximum induction. It is suggested that the differential induction of GSH S-transferase activities by BHT towards different substrates may be due to the differences in the induction of the constituent subunits of GSH S-transferases.
摘要
当将丁基羟基甲苯（BHT）给予大鼠时，发现大鼠肝脏谷胱甘肽S-转移酶最小的亚基Ya（分子量22,000）诱导程度最大。有人提出，BHT对不同底物的谷胱甘肽S-转移酶活性的差异诱导可能是由于谷胱甘肽S-转移酶组成亚基诱导的差异所致。
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