Laycock J R, Coakham H B, Silver I A, Walters F J
Neurol Res. 1984 Mar-Jun;6(1-2):75-8. doi: 10.1080/01616412.1984.11739668.
A multitipped oxygen electrode has been used to measure cortical surface oxygen tensions in the sheep. A histogram of the pattern of supply of oxygen to cortical tissue within the microcirculation during normal conditions is presented. Systemic arterial pressure was reduced to a mean of 30 mmHg with either Adenosine or ATP, and further oxygen tension measurements undertaken. The oxygen histogram was shifted to the left in these circumstances, and there was an increase in the frequency of occurrence of very low tissue oxygen tensions. This suggests that the use of these agents to induce profound hypotension may be associated with significant ischaemia within the microcirculation.
一种多尖端氧电极已被用于测量绵羊大脑皮质表面的氧张力。文中呈现了正常情况下微循环中向皮质组织供氧模式的直方图。使用腺苷或三磷酸腺苷将体动脉压降至平均30毫米汞柱，并进一步进行氧张力测量。在这些情况下，氧直方图向左移动，并且组织氧张力极低的出现频率增加。这表明使用这些药物诱导深度低血压可能与微循环内的显著缺血有关。
