Okayasu I, Mizutani H, Kurihara H, Yanagisawa F
Cancer. 1984 Nov 1;54(9):1841-4. doi: 10.1002/1097-0142(19841101)54:9<1841::aid-cncr2820540912>3.0.co;2-k.
Cases of systemic lupus erythematosus, systemic sclerosis, periarteritis nodosa, and dermato- and polymyositis autopsied in Japan during a recent, 7-year period (1972-1978) were studied to assess the incidence of cancer as a complication. In comparison with the other three groups, cases of dermato- and polymyositis (DP) showed quite a high incidence of malignancy: 53 of 99 for males (53.5%) and 36 of 139 for females (25.9%). In patients older than 50 years of age cancer was recognized in the autopsies of 65.7% of males and 38.2% of females with DP. The stomach was both the primary site and had the highest incidence of cancers in DP (62.3% males, 27.8% females). It was concluded that DP has a strong association with the development of cancer, particularly gastric carcinoma, in Japan.
对日本最近7年（1972 - 1978年）尸检的系统性红斑狼疮、系统性硬化症、结节性多动脉炎以及皮肌炎和多发性肌炎病例进行研究，以评估癌症作为并发症的发生率。与其他三组相比，皮肌炎（DP）病例的恶性肿瘤发生率相当高：男性99例中有53例（53.5%），女性139例中有36例（25.9%）。在50岁以上的患者中，皮肌炎男性尸检中有65.7%、女性中有38.2%发现患有癌症。胃既是皮肌炎中癌症的主要发病部位，其发生率也最高（男性为62.3%，女性为27.8%）。得出的结论是，在日本，皮肌炎与癌症尤其是胃癌的发生有很强的关联。
