Tarsy D
Psychiatr Clin North Am. 1984 Sep;7(3):453-71.
Antipsychotic drugs produce several neurologic complications including acute dyskinesia, parkinsonism, neuroleptic malignant syndrome, akathisia, and tardive dyskinesia. Despite increased awareness of these syndromes, they continue to be underdiagnosed among patients receiving antipsychotic drugs. The clinical features, possible pathophysiologic mechanisms, and treatment of these conditions are discussed in this review.
抗精神病药物会引发多种神经并发症,包括急性运动障碍、帕金森症、抗精神病药物恶性综合征、静坐不能和迟发性运动障碍。尽管对这些综合征的认识有所提高,但在接受抗精神病药物治疗的患者中,它们仍经常被漏诊。本文综述讨论了这些病症的临床特征、可能的病理生理机制及治疗方法。