Hadziselimović F, Hecker E, Herzog B
Urol Res. 1984;12(3):171-4. doi: 10.1007/BF00255917.
This prospective study conducted on 24 children, who have now reached adulthood, was undertaken to determine the value of testicular biopsies in cryptorchidism relative to fertility prognosis. A significant correlation between the number of germ cells in the biopsy and sperm count was found to exist (p less than 5%). Thus, the testicular biopsy performed during orchiopexy was found to have a prognostic value. The hormonal findings (LH, FSH) suggest that in cryptorchid adults impaired Leydig cell function exists only when serious tubular damage is present. Because of its prognostic value with respect to fertility and the probability of discovering carcinoma in situ cells, it is strongly recommended that a testicular biopsy is performed in cryptorchid boys.
这项针对24名现已成年的儿童进行的前瞻性研究，旨在确定隐睾症患者睾丸活检对于生育预后的价值。研究发现活检中生殖细胞数量与精子计数之间存在显著相关性（p小于5%）。因此，发现睾丸固定术中进行的睾丸活检具有预后价值。激素检查结果（促黄体生成素、促卵泡生成素）表明，在隐睾成年患者中，仅当存在严重的曲细精管损伤时，才会出现睾丸间质细胞功能受损。鉴于其对生育的预后价值以及发现原位癌细胞的可能性，强烈建议对隐睾症男孩进行睾丸活检。
