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Plasto-elasticity and tableting of paracetamol, Avicel and other powders.

作者信息

Malamataris S, Bin Baie S, Pilpel N

出版信息

J Pharm Pharmacol. 1984 Sep;36(9):616-7. doi: 10.1111/j.2042-7158.1984.tb04909.x.

Abstract

The plasto-elasticity of mixtures of paracetamol and Avicel powders and the tensile strengths of their tablets varied with the sizes of the particles and with the compositions of the mixtures. Tests made on these and other tablets showed that the logarithms of their strengths were inversely proportional to the ratios of the samples' elastic recovery: plastic compression; they exhibited lamination or capping when this ratio was greater than 9.

摘要

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