The hydroxy-hexanydronaphthoxazines: a new group of very potent and selective dopamine agonists.
作者信息
Horn A S, Hazelhoff B, Dijkstra D, de Vries J B, Mulder T B, Timmermans P, Wynberg H
出版信息
J Pharm Pharmacol. 1984 Sep;36(9):639-40. doi: 10.1111/j.2042-7158.1984.tb04918.x.
Abstract
Replacement of the pyrrole ring system in the dopaminergic oxaergolines (e.g. RU 29717) by a phenolic OH group leads to the hydroxy-hexahydronaphthoxazines, a new group of potent dopamine agonists which exhibit increased selectivity due to their lower affinity for adrenergic and 5-HT receptors.
摘要
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