Langrehr D, Agoston S, Sia R
Acta Anaesthesiol Belg. 1984 Jun;35(2):165-87.
A review is given of the pharmacodynamic effects of Ketamine and the commonly used Benzodiazepines especially regarding the clinical application of the substances in combination as socalled ataranalgesia. The literature as well as own experimental results show the advantages of ataranalgetic combinations for induction and maintenance of general anesthesia. Special comment is given for new results about the reversal of hypnotic action by means of 4-aminopyridine.
本文综述了氯胺酮和常用苯二氮䓬类药物的药效学作用，尤其关注这些药物联合使用时在所谓“安定镇痛”临床应用方面的情况。文献以及我们自己的实验结果均表明，安定镇痛联合用药在全身麻醉诱导和维持方面具有优势。文中特别提及了关于通过4-氨基吡啶逆转催眠作用的新研究结果。
