Vasilev N, Mikhaĭlov I, Ganchev S, Makaveeva V, Vylcheva V
Arkh Patol. 1984;46(8):29-34.
Seven ovarian tumours (3 mature teratomas, 2 strumas with malignancy 2 strumal carcinoids) have been examined histologically, hystochemically and electron-microscopically. It is shown that the cell composition of the strumal teratoma tissue is very similar to that of the ectopic thyroid. The follicular cells may proliferate either into the benign tumour (apudoma) or typical thyroid carcinoma. Parafollicular cells may give rise to C-cell hyperplasia with the amyloid deposits in the stroma. The so-called strumal carcinoid of the ovary represents probably the C-cell tumour. Its "strumal" component may be considered as preexisting follicles invaded by tumour apudocytes or as the site of tumour origin displaying the pattern of a non-medullary thyroid apudoma.
对7例卵巢肿瘤(3例成熟畸胎瘤、2例恶性甲状腺肿、2例甲状腺肿类癌)进行了组织学、组织化学和电子显微镜检查。结果表明,甲状腺肿性畸胎瘤组织的细胞组成与异位甲状腺非常相似。滤泡细胞可增殖形成良性肿瘤(APUD瘤)或典型甲状腺癌。滤泡旁细胞可导致C细胞增生,并伴有间质淀粉样沉积。所谓的卵巢甲状腺肿类癌可能代表C细胞瘤。其“甲状腺肿”成分可被视为被肿瘤APUD细胞侵入的原有滤泡,或被视为显示非髓样甲状腺APUD瘤模式的肿瘤起源部位。