Behavioral and electrophysiological manifestations of bombesin: excessive grooming and elimination of sleep.
作者信息
Rasler F E
出版信息
Brain Res. 1984 Oct 29;321(1):187-91. doi: 10.1016/0006-8993(84)90700-5.
PMID:6149791
Abstract
The effect of bombesin, applied intraventricularly in the rat, was examined with regard to the central control of behavior and arousal. Infusion of 1.0 micrograms bombesin produced stereotypic grooming activity and completely eliminated observable sleep. EEG frequency analysis confirmed the absence of sleep and demonstrated normal waking patterns during behavioral stereotypy. These results support a possible physiologic function for bombesin-like peptides in grooming and the sleep-waking cycle.
摘要
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