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[前室间动脉单支狭窄所致不稳定型心绞痛(87例)。内科及外科治疗结果]

[Unstable angina caused by monotruncular stenosis of the anterior interventricular artery (87 cases). Results of medical and surgical treatment].

作者信息

Brau J, Bénacerraf A, Lévy A, Veau P, Rakotovao A

出版信息

Arch Mal Coeur Vaiss. 1984 Nov;77(12):1351-8.

PMID:6150692
Abstract

The aim of this study was to compare the medium-term results of medical therapy and aortocoronary bypass surgery in 87 patients selected on the following criteria: Clinical: unstable angina, defined as effort and/or resting angina appearing for the first time or increasing in severity within the previous 3 months, the last attack of chest pain occurring less than 8 days before admission to the Coronary Care Unit, with no signs of myocardial infarction before hospital admission and at coronary angiography. Coronary angiography: proximal isolated left anterior descending artery stenosis (greater than 70%). Thirty five patients were treated medically and 52 underwent coronary bypass surgery on the LAD artery: the results were compared at 18 and 24 months. Six patients were lost to follow-up, 2 from the medical group; the other 33 patients comprised group A. Four surgical patients were lost to follow-up, the other 48 patients comprised group B. The two groups had comparable clinical and epidemiological features. They differed in the incidence of hypertension which was more common in group A (p less than 0.01), in the better quality of the distal LAD artery in group B (p less than 0.01), and in the coexistence of less than 50% stenosis on the right coronary and left circumflex arteries which was commoner in group A (p less than 0.05). The mean follow-up period was comparable in the two groups (group A: 20.5 +/- 4.6 months; group B: 19.8 +/- 5.5 months).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究旨在比较87例符合以下标准患者的药物治疗和主动脉冠状动脉搭桥手术的中期结果:临床标准:不稳定型心绞痛,定义为在前3个月内首次出现或严重程度增加的劳力性和/或静息性心绞痛,入院至冠心病监护病房前最后一次胸痛发作距入院时间少于8天,入院前及冠状动脉造影时无心肌梗死迹象。冠状动脉造影标准:孤立性左前降支近端狭窄(大于70%)。35例患者接受药物治疗,52例接受左前降支冠状动脉搭桥手术:在18个月和24个月时比较结果。6例患者失访,其中2例来自药物治疗组;其余33例患者组成A组。4例手术患者失访,其余48例患者组成B组。两组具有可比的临床和流行病学特征。他们在高血压发病率方面存在差异,A组更常见(p<0.01);B组左前降支远端血管质量更好(p<0.01);右冠状动脉和左旋支动脉存在小于50%狭窄的情况在A组更常见(p<0.05)。两组的平均随访期相当(A组:20.5±4.6个月;B组:19.8±5.5个月)。(摘要截短至250字)

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