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精索静脉曲张:临床治疗还是手术治疗?

Varicocele: clinical or surgical treatment?

作者信息

Netto Júnior N R, Fakiani E P, Lemos G C

出版信息

Int J Fertil. 1984;29(3):164-7.

PMID:6152255
Abstract

Varicocele, known as the most common cause of male infertility, has usually been treated surgically and, although successful results have been reported, its therapeutic efficiency has been questioned. Sixty-six infertile men with varicocele were under treatment within the period December, 1971-1981. Thirty-eight underwent surgical correction (varicocelectomy) and twenty-eight received only medical treatment. The spermograms of all the patients reported sperm counts, percentage of general motility, percentage of grade III motile sperm (rapid and directional movements) and percentage of oval forms, before and after the treatment. The results showed that there was an improvement in all the spermogram parameters in both groups. Except for one variable all the others failed to show a significant difference by statistical analysis between both treatments, however, the surgical treatment resulted in higher values when compared to the medical one. Pregnancy rates, while higher for the surgical group, was not statistically different in both groups. The medical treatment showed to be effective in elective cases. Nevertheless, the surgical treatment remains the better choice in the treatment of subfertility associated to varicocele.

摘要

精索静脉曲张是男性不育最常见的原因,通常采用手术治疗。尽管有成功的报道,但它的治疗效果一直受到质疑。1971年12月至1981年期间,66名患有精索静脉曲张的不育男性接受了治疗。38人接受了手术矫正(精索静脉结扎术),28人仅接受了药物治疗。所有患者的精液分析报告了治疗前后的精子计数、总活力百分比、Ⅲ级活动精子(快速和定向运动)百分比以及椭圆形精子百分比。结果表明,两组患者的所有精液分析参数均有改善。除一个变量外,其他所有变量经统计学分析在两种治疗方法之间均未显示出显著差异,然而,与药物治疗相比,手术治疗的各项数值更高。手术组的妊娠率更高,但两组之间在统计学上并无差异。药物治疗在选择性病例中显示有效。尽管如此,手术治疗仍是与精索静脉曲张相关的亚生育治疗的更好选择。

相似文献

1
Varicocele: clinical or surgical treatment?精索静脉曲张:临床治疗还是手术治疗?
Int J Fertil. 1984;29(3):164-7.
2
Varicocele: medical and surgical treatment.精索静脉曲张:医学与外科治疗
Int J Fertil. 1987 Nov-Dec;32(6):432-5.
3
Is varicocelectomy indicated in subfertile men with clinical varicoceles who have asthenospermia or teratospermia and normal sperm density?对于患有临床精索静脉曲张、弱精子症或畸形精子症且精子密度正常的不育男性,精索静脉曲张切除术是否适用?
Int J Urol. 2007 Aug;14(8):729-32. doi: 10.1111/j.1442-2042.2007.01786.x.
4
[Current approach to therapy for male infertility in patients with varicocele].[精索静脉曲张患者男性不育症的当前治疗方法]
Ter Arkh. 2012;84(10):56-61.
5
The varicocele and male infertility.精索静脉曲张与男性不育症。
Urol Clin North Am. 1981 Feb;8(1):41-51.
6
Microsurgical varicocelectomy for isolated asthenospermia.显微外科精索静脉曲张切除术治疗单纯弱精子症
J Urol. 2008 Nov;180(5):2129-32. doi: 10.1016/j.juro.2008.07.046. Epub 2008 Sep 18.
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Hinyokika Kiyo. 2004 Aug;50(8):549-52.
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[Laparoscopic varicocele ligation. The comparative assessment of artery-ligating and artery-preserving varicocelectomy].[腹腔镜精索静脉曲张结扎术。动脉结扎与保留动脉的精索静脉切除术的对比评估]
Wiad Lek. 2001;54(11-12):621-31.
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Natural history of varicocele management in the era of intracytoplasmic sperm injection.卵胞浆内单精子注射时代精索静脉曲张治疗的自然史
Fertil Steril. 2008 Dec;90(6):2251-6. doi: 10.1016/j.fertnstert.2007.10.071. Epub 2008 Jan 28.
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Effect of infertility duration on postvaricocelectomy sperm counts and pregnancy rates.
Urology. 2009 Apr;73(4):767-71. doi: 10.1016/j.urology.2008.06.014. Epub 2009 Feb 11.