转录调控和酶失活在大肠杆菌氨甲酰磷酸合成酶合成中的作用。
Role of transcriptional regulation and enzyme inactivation in the synthesis of Escherichia coli carbamoylphosphate synthase.
作者信息
Piérard A, Lissens W, Halleux P, Cunin R, Glansdorff N
出版信息
J Bacteriol. 1980 Jan;141(1):382-5. doi: 10.1128/jb.141.1.382-385.1980.
Abstract
The question of posttranscriptional control during cumulative repression of Escherichia coli carbamoylphosphate synthase has been examined by following the kinetics of repression and by comparing messenger ribonucleic acid and enzyme levels after growth under various conditions. The data provide no evidence for control of synthesis at a level other than transcription. They suggest, however, that enzyme inactivation (or turnover) plays a significant role in the establishment of repressive conditions.
摘要
通过追踪阻遏动力学以及比较在各种条件下生长后信使核糖核酸和酶的水平，对大肠杆菌氨甲酰磷酸合酶累积阻遏过程中的转录后调控问题进行了研究。数据没有提供除转录水平之外其他合成调控的证据。然而，它们表明酶的失活（或周转）在建立阻遏条件中起重要作用。
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