Agrup G, Hansson C, Rorsman H, Rosengren E
Acta Derm Venereol. 1980;60(1):63-4.
5-S-Cysteinyldopa, dopa, and dopamine levels were determined by HPLC and electrochemical detection in serum, urine, kidney, spleen, heart, and sympathetic ganglion of guinea-pig. The kidney showed high levels of 5-S-cysteinyldopa, but also of dopa and dopamine, thus demonstrating the role of the renal ti-sue in the excretion of these substances. The concentrations found in spleen and heart may indicate specific catechol-containing structures in these organs.
采用高效液相色谱法和电化学检测法测定了豚鼠血清、尿液、肾脏、脾脏、心脏和交感神经节中5-S-半胱氨酰多巴、多巴和多巴胺的水平。肾脏中5-S-半胱氨酰多巴、多巴和多巴胺水平均较高,从而证明了肾脏组织在这些物质排泄中的作用。在脾脏和心脏中发现的浓度可能表明这些器官中存在特定的含儿茶酚结构。