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糖尿病和肝硬化中的海藻糖酶活性。

Trehalase activity in diabetes mellitus and in cirrhosis of the liver.

作者信息

Stork A, Fabian E, Kozáková B, Fabianová J

出版信息

Acta Univ Carol Med Monogr. 1977(78 Pt 2):36-40.

PMID:615463
Abstract

Trehalase (an enzyme decomposing the disaccharide trehalose) activity was studied in 29 healthy subjects, 25 patients with cirrhosis and 112 diabetics. Mean trehalase activity was 176 +/- 11 units in the control group, 647 +/- 421 units in the patients with cirrhosis and 467 +/- 239 units in diabetics. The differences between the control group on the one hand and the groups with cirrhosis and diabetes on the other were statistically significant. The results show that the organism, under pathological conditions, makes far greater use of its enzymatic apparatus to assure its basic requirements, but the scatter of the values is so great that the determination of trehalase has no discriminative value in individual cases.

摘要

对29名健康受试者、25名肝硬化患者和112名糖尿病患者的海藻糖酶(一种分解二糖海藻糖的酶)活性进行了研究。对照组的平均海藻糖酶活性为176±11单位,肝硬化患者为647±421单位,糖尿病患者为467±239单位。一方面对照组与另一方面肝硬化组和糖尿病组之间的差异具有统计学意义。结果表明,在病理条件下,机体为确保其基本需求而更多地利用其酶系统,但数值的离散度非常大,以至于海藻糖酶的测定在个别病例中没有鉴别价值。

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Trehalase activity in diabetes mellitus and in cirrhosis of the liver.糖尿病和肝硬化中的海藻糖酶活性。
Acta Univ Carol Med Monogr. 1977(78 Pt 2):36-40.
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