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灵长类动物覆盖式自体颗粒骨移植的血管再生与愈合

Revascularization and healing of onlay particulate autologous bone grafts in primates.

作者信息

Fonseca R J, Clark P J, Burkes E J, Baker R D

出版信息

J Oral Surg. 1980 Aug;38(8):572-7.

PMID:6156232
Abstract

Two sizes of bone chips were compared to determine the size that revascularizes faster and what effect this has on the resorption of the graft. To accomplish this, autologous chips of iliac corticocancellous bone of either 2 X 2 X 2 mm or 5 X 5 X 2 mm were placed in the mandibular cortex of monkeys bilaterally. In general, the small-particle graft was quicker to revascularize, showed more osteoclastic activity, and therefore resorbed much more quickly and completely than did the large-particle graft. The resultant net gain in alveolar ridge contour was, therefore, less with the small-particle grafts.

摘要

比较了两种尺寸的骨块,以确定哪种尺寸的骨块血管再生更快,以及这对移植物吸收有何影响。为实现这一目的,将尺寸为2×2×2毫米或5×5×2毫米的自体髂骨皮质松质骨块双侧植入猴子的下颌骨皮质中。一般来说,小颗粒移植物血管再生更快,显示出更多的破骨细胞活性,因此比大颗粒移植物吸收得更快、更完全。因此,小颗粒移植物在牙槽嵴轮廓上的最终净增益较小。

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