Filczewski M, Oledzka K, Szymańska-Kosmala M, Bogucka E
Acta Physiol Pol. 1980 Mar-Apr;31(2):201-8.
The following haemodynamic values were determined in anaesthetized mongrel dogs: heart rate, systolic blood pressure in the ascending aorta, left ventricular pressure at the peak dp/dt, left ventricular end-diastolic pressure, time interval from Q in ECG to the onset of the systolic wave of dp/dt, time interval from Q in ECG to peak dp/dt, maximum rate of left ventricular pressure rise, femoral arterial flow, and certain indices of left ventricular contractility. It was concluded from the results of these experiments that infusion of a modified gelatin solution Fluigel prevented haemodynamic and metabolic changes produced by experimental hypovolaemia more effectively than infusion of Plasmagel.
心率、升主动脉收缩压、左心室压力变化最大速率(dp/dt)峰值时的左心室压力、左心室舒张末期压力、心电图Q波至dp/dt收缩波起始的时间间隔、心电图Q波至dp/dt峰值的时间间隔、左心室压力上升最大速率、股动脉血流量以及左心室收缩性的某些指标。从这些实验结果得出的结论是,输注改良明胶溶液Fluigel比输注Plasmagel更有效地预防了实验性低血容量引起的血流动力学和代谢变化。