正常衰老、老年痴呆和慢性酒精中毒患者大脑中的生物胺
Biogenic amines in human brain in normal aging, senile dementia, and chronic alcoholism.
作者信息
Carlsson A, Adolfsson R, Aquilonius S M, Gottfries C G, Oreland L, Svennerholm L, Winblad B
出版信息
Adv Biochem Psychopharmacol. 1980;23:295-304.
PMID:6156586
Abstract
Postmortem examination of various brain regions of cases without known brain pathology showed an age-related decrease in the levels of dopamine in the nigrostriatal system, of norepinephrine in the hippocampus, and of 5-HT in the gyrus cinguli but an increase of 5-HT in the medulla oblongata and of MAO B in several brain regions.
摘要
对无已知脑部病变病例的各个脑区进行尸检发现，黑质纹状体系统中的多巴胺水平、海马体中的去甲肾上腺素水平以及扣带回中的5-羟色胺水平随年龄增长而降低，但延髓中的5-羟色胺水平以及几个脑区中的单胺氧化酶B水平有所升高。
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