Strecker E P, Novak G R, James A E
Eur Neurol. 1977;16(1-6):203-12. doi: 10.1159/000114901.
Transfer of radioactively labelled albumin from the cerebrospinal fluid (CSF) to the blood was monitored in 15 dogs with normal cisternograms and in 8 dogs with induced communicating hydrocephalus. Blood concentration curves alone are of limited value and give less than satisfactory information about CSF distribution spaces and were corrected for albumin disappearance from the blood to other compartments. The transit time in animals with hydrocephalus was much greater than in normals and entry into the intravascular compartment was delayed. Mathematical analysis to the indicator movements appears to offer understanding about CSF compartments and transfer of molecules in different types of hydrocephalus.
在15只脑池造影正常的犬和8只诱发交通性脑积水的犬中监测了放射性标记白蛋白从脑脊液（CSF）到血液的转移情况。仅血液浓度曲线价值有限，关于脑脊液分布空间提供的信息不尽人意，并且针对白蛋白从血液向其他腔室的消失情况进行了校正。脑积水动物的转运时间比正常动物长得多，进入血管腔室也延迟了。对示踪剂移动的数学分析似乎有助于了解不同类型脑积水中脑脊液腔室和分子的转移情况。
