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正常猫和感染隐匿猫圆线虫的猫的血清蛋白

Serum proteins in normal cats and cats infected with Aelurostrongylus abstrusus.

作者信息

Barsanti J A, Hubbell J

出版信息

Am J Vet Res. 1980 May;41(5):775-8.

PMID:6157342
Abstract

Serum proteins were evaluated by cellulose acetate electrophoresis in cats prior to and every 2 weeks for 24 weeks after oral infection with third stage larvae of Aelurostrongylus abstrusus. Evaluation of electrophoretograms was standardized by determination of electrophoretic migration ratios. Six fractions of serum proteins were consistently identified: albumin and alpha 1, alpha 2, beta 1, beta 2, and gamma globulin. Relative and absolute concentrations of each serum protein fraction were determined. The only changes found were a decrease in concentration of alpha globulins and an increase in concentration of beta 1 globulins. These changes were mild, however, so that the the concentrations for infected cats were still within 1 SD of the control concentrations. Apparently serum electrophoresis is not a useful diagnostic test for aelurostrongylosis.

摘要

在用隐匿猫圆线虫第三期幼虫经口感染猫之前以及感染后的24周内,每2周通过醋酸纤维素电泳对血清蛋白进行评估。通过测定电泳迁移率对电泳图谱的评估进行标准化。始终鉴定出六种血清蛋白组分:白蛋白、α1、α2、β1、β2和γ球蛋白。测定了每种血清蛋白组分的相对浓度和绝对浓度。唯一发现的变化是α球蛋白浓度降低和β1球蛋白浓度升高。然而,这些变化很轻微,以至于感染猫的浓度仍在对照浓度的1个标准差范围内。显然,血清电泳对猫圆线虫病不是一种有用的诊断测试。

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