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[肝脏再生早期RNA合成及向细胞质分泌的放射自显影研究]

[Autoradiographic study of RNA synthesis and secretion into the cytoplasm during the early stages of liver regeneration].

作者信息

Gerasimova T B, Obolenskaia M Iu, Platonov O M

出版信息

Tsitol Genet. 1980 May-Jun;14(3):77-82.

PMID:6158152
Abstract

Autoradiographic experiments with regeneration of rat liver showed that RNA transport from nucleus to cytoplasm occurs more quickly in 3h following partial hepatectomy while the total RNA synthesis increases insignificantly. Nucleolar RNA synthesis at this time grows in some hepatocytes and decreases in others though it does not differ on the average from the control one. By the 6th h after partial hepatectomy total RNA synthesis significantly increases simultaneously with the acceleration of RNA transport to cytoplasm. Nucleolar RNA synthesis intensifies in all hepatocytes.

摘要

用大鼠肝脏再生进行的放射自显影实验表明,部分肝切除术后3小时内,RNA从细胞核向细胞质的转运更快,而总RNA合成增加不明显。此时,一些肝细胞的核仁RNA合成增加,另一些肝细胞的核仁RNA合成减少,不过平均而言与对照无差异。部分肝切除术后第6小时,总RNA合成显著增加,同时RNA向细胞质的转运加速。所有肝细胞的核仁RNA合成均增强。

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