Araujo V C, Araujo N S, Mariano M
J Pathol. 1980 Oct;132(2):181-9. doi: 10.1002/path.1711320208.
A study was made of the vascular permeability changes occurring in the dental pulp of rat teeth subjected to trauma of the occlusal surface with a special steel burr. The vascular response was measured by leakage of 131I-labelled human serum albumin and of colloidal carbon. The effect of a variety of inhibitors of increased vascular permeability was observed. The results obtained support the hypothesis that in the model studied the vascular response of the dental pulp is mediated by the sequential release of histamine and 5-HT, kinins and prostaglandins.
用特制钢钻对大鼠牙齿咬合面造成创伤，研究牙髓中发生的血管通透性变化。通过131I标记的人血清白蛋白和胶体碳的渗漏来测量血管反应。观察了多种血管通透性增加抑制剂的作用。所得结果支持这样的假说：在所研究的模型中，牙髓的血管反应是由组胺、5-羟色胺、激肽和前列腺素的相继释放介导的。
